BeschreibungAdvances in the biomedical sciences, especially genomics, proteomics, and metabolomics, taken together with the expanding use of electronic health records, are radically changing the IT infrastructure and software applications needed to support the transfer of knowledge from bench to bedside. Pediatric Biomedical Informatics: Computer Applications in Pediatric Research describes the core resources in informatics necessary to support biomedical research programs and how these can best be integrated with hospital systems to receive clinical information that is necessary to conduct translational research.The focus is on the authors' recent practical experiences in establishing an informatics infrastructure in a large research-intensive children's hospital. This book is intended for translational researchers and informaticians in pediatrics, but can also serve as a guide to all institutions facing the challenges of developing and strengthening informatics support for biomedical research. The first section of the book discusses important technical challenges underlying computer-based pediatric research, while subsequent sections discuss informatics applications that support biobanking and a broad range of research programs. Pediatric Biomedical Informatics provides practical insights into the design, implementation, and utilization of informatics infrastructures to optimize care and research to benefit children. Dr. John Hutton is the Vice President and Director of Biomedical Informatics at Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. He is also Professor of Pediatrics and Associate Dean for Information Services at the University of Cincinnati College of Medicine.
InhaltsverzeichnisPediatric Electronic Health Records and Research.
Interfaces and Data Transmission Standards.
Data Storage and Access Management.
Institutional Cybersecurity in a Clinical Research Setting.
Protecting Privacy in the Child's Electronic Health Record.
Research Patient Data Warehousing.
Biobanking in Pediatric Research.
EHR-linked Registries for Studies of Populations.
Natural Language Processing - The Basics.
Natural Language Processing: Applications in Pediatric Research.
Informatics and Decision Support.
Support of Perinatal and Neonatal Research.
Informatics Support of Outcomes Measures.
Patient Safety - Automated Detection and Reporting.
Network Analysis in Translational Research.
Orphan Diseases, Bioinformatics and Drug Discovery.
Transcriptional Networks - Control of Lung Maturation.
Defining Genetic Blueprints - Kidney and Craniofacial Development.
From SNP Genotyping to Improved Pediatric Healthcare.
Genetic Variation and Gene Discovery.
PressestimmenFrom the reviews: "This text concentrates on pediatric applications of data mining and knowledge discovery of biomedical informatics data, and considers practical network questions to ensure privacy and quick access to that data. ... This book is a meaningful resource for understanding the current breadth and depth of bioinformatics research applications that are improving pediatric healthcare and support. It is a recommended text for researchers in the field." (Michael Goldberg and R. Goldberg, Computing Reviews, August, 2013)
Untertitel: Computer Applications in Pediatric Research. 2012. Auflage. Previously published in hardcover. Sprache: Englisch.
Erscheinungsdatum: Januar 2015
Seitenanzahl: 420 Seiten