Algorithms on Strings, Trees and Sequences

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Mai 1997



String algorithms are a traditional area of study in computer science. In recent years their importance has grown dramatically with the huge increase of electronically stored text and of molecular sequence data (DNA or protein sequences) produced by various genome projects. This book is a general text on computer algorithms for string processing. In addition to pure computer science, the book contains extensive discussions on biological problems that are cast as string problems, and on methods developed to solve them. It emphasises the fundamental ideas and techniques central to today's applications. New approaches to this complex material simplify methods that up to now have been for the specialist alone. With over 400 exercises to reinforce the material and develop additional topics, the book is suitable as a text for graduate or advanced undergraduate students in computer science, computational biology, or bio-informatics. Its discussion of current algorithms and techn iques also makes it a reference for professionals.


From the contents: Part I. Exact String Matching: The Fundamental String Problem: 1. Exact matching: fundamental preprocessing and first algorithms 2. Exact matching: classical comparison-based methods 3. Exact matching: a deeper look at classical methods 4. Semi-numerical string matching; Part II. Suffix Trees And Their Uses: 5. Introduction to suffix trees 6. Linear time construction of suffix trees 7. First applications of suffix trees 8. Constant time lowest common ancestor retrieval 9. More applications of suffix trees; Part III. Inexact Matching, Sequence Alignment, And Dynamic Programming: 10. The importance of (sub)sequence comparison in molecular biology 11. Core string edits, alignments, and dynamic programming 12. Refining core string edits and alignments 13. Extending the core problems 14. Multiple string comparison: the Holy Grail 15. Sequence database and their uses: the motherlode; Part IV. Currents, Cousins And Cam eos: 16. Maps, mapping, sequencing and superstrings 17. Strings and evolutionary trees 18. Three short topics 19. Models of genome-level mutations


'The readers of this book will be serious programmers, but of course anybody working in bio-computing will find the book of immense practical, scientific and commercial importance ... you should get the book, whether you want to do some string processing, fundamental computing research, or want to impress a biotech firm.' Harold Thimbleby, Times Higher Education Supplement '... could well be used as the basis for a graduate-level course, particularly as it contains over 400 exercises to reinforce presented material and to develop further topics. It is recommended most highly.' P. Gibbons, Zentralblatt fur Mathematik
EAN: 9780521585194
ISBN: 0521585198
Untertitel: Computer Science and Computational Biology. 145 diagrams. Sprache: Englisch.
Verlag: Cambridge University Pr.
Erscheinungsdatum: Mai 1997
Seitenanzahl: 554 Seiten
Format: gebunden
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