Glycoproteins I

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Juli 1995



Part I covers modern advances in the determination of
glycoprotein structure and in the biosynthesis of mammalian,
bacterial, yeast, plant and insect glycoproteins. There are also
two chapters on functional aspects (glycoprotein hormones and
The content of the volume is very comprehensive in that, most
contributors have focussed on discussing, in depth, the wealth
of most recent advances in their field, and referring to previous
reviews of older work for background information. This method can
effectively produce a very wide subject coverage in a smaller
number of chapters/volumes. The volume is an important
information source for all glycobiologist researchers (senior
investigators, post-doctoral fellows and graduate students), and
as a good, comprehensive, reference text for scientists working in
the life sciences.


History of glycoprotein research, J. Montreuil; primary structure of glycoprotein glycans, J.F.G. Vliegenthart and J. Montreuil; 3D-structure - -X-ray, C. Cambillau; -NMR and computer calculations, S.W. Homans; chemical synthesis of glycopeptides, H. Paulsen et al; biosynthesis introduction, H. Schachter; the coenzymatic role of phosphodolichols, F. Hemming; from Glc3Man9GlcNAc2-protein to Man5GlcNAc2-protein - transfer "en bloc" and processing, A. Verbert; glycosyltransferases involved in the synthesis of N-glycan antennae, H. Schachter; biosynthesis of O-glycans of the N-acetylgalactosamine-alpha-ser/thr linkage type, I. Brockhausen; gene regulation of terminal glycosylation, M.C. Glick; substrate level controls for N-glycan assembley, H. Schachter; compartmentation of glycoprotein biosynthesis, J. Roth; molecular basis of antigenic specificity in the ABO, H and Lewis blood-group systems, W.M. Watkins; the role of polypeptide in the biosynthesis of protein-linked oligosaccharides, R.T. Camphausen et al; how can N-linked glycosylation and processing inhibitors be used to study carbohydrate synthesis and function?, Y.T. Pan and A.D. Elbein; bacterial glycoproteins, M. Sumper and F.T. Wieland; protein glycosylation in yeast, L. Lehle and W. Tanner; O-glycosylation in plants, F.M. Klis; N-glycosylation of plant protein, A. Sturm; protein glycosylation in insects, L. Marz et al; the glycoprotein hormone family, M. Bielinska and I. Boime; carbohydrate moieties of vertebrate collagens, M.E. Noelken and G. Hudson.


...this book, edited by three of the seminal figures in the Glycoprotein world, conceals an amazingly comprehensive first volume in a three-volume series...researchers hoping to contribute to the further development of this exciting field, without at least the first volume...do so at their peril! Carbohydrates in Europe
EAN: 9780444820754
ISBN: 0444820752
Untertitel: Sprache: Englisch.
Erscheinungsdatum: Juli 1995
Seitenanzahl: 640 Seiten
Format: kartoniert
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