Wildlife and Emerging Zoonotic Diseases: The Biology, Circumstances and Consequences of Cross-Species Transmission

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August 2007



This volume provides an overview of the processes of zoonotic viral emergence, the intricacies of host/virus interactions, and the distinct role of biological transitions and modifying factors. The process of emergence is conceptualized as two transition stages which are common and required for all disease emergence, (1) human contact with the infectious agent and (2) cross-species transmission of the agent, and two transition stages which are not required for emergence and appear unavailable to many zoonotic pathogens, (3) sustained human-to-human transmission and (4) genetic adaptation to the human host. The latter two transitions are presumably prerequisites for the pandemic emergence of a pathogen. The themes introduced herein are amplified and explored in detail by the contributors to this volume. Each author explores the mechanisms and unique circumstances by which evolution, biology, history, and current context have contrived to drive the emergence of different zoonotic agents by a series of related events; although recognizable similarities exist among the events leading to emergence the details and circumstances are never repetitive.


Introduction: Conceptualizing and Partitioning the Emergence Process of Zoonotic Viruses from Wildlife to Humans.- Infectious Disease Modeling and the Dynamics of Transmission.- The Evolutionary Genetics of Viral Emergence.- Influenza Viruses in Animal Wildlife Populations.- Overviews of Pathogen Emergence: Which Pathogens Emerge, When and Why?.- Infection and Disease in Reservoir and Spillover Hosts: Determinants of Pathogen Emergence.- Henipaviruses: Emerging Paramyxoviruses Associated with Fruit Bats.- Emergence of Lyssaviruses in the Old World: The Case of Africa.- Tuberculosis: A Reemerging Disease at the Interface of Domestic Animals and Wildlife.- Emergence and Persistence of Hantaviruses.- Arenaviruses.- Ecological Havoc, the Rise of White-Tailed Deer, and the Emergence of Amblyomma americanum-Associated Zoonoses in the United States.- Bats, Civets and the Emergence of SARS.- Poxviruses and the Passive Quest for Novel Hosts.- Ebolavirus and Other Filoviruses.- Pre-spillover Prevention of Emerging Zoonotic Diseases: What Are the Targets and What Are the Tools?.- Impediments to Wildlife Disease Surveillance, Research, and Diagnostics.- Collaborative Research Approaches to the Role of Wildlife in Zoonotic Disease Emergence.- Surveillance and Response to Disease Emergence.
EAN: 9783540709619
ISBN: 3540709614
Untertitel: 'Current Topics in Microbiology and Immunology'. 2007. Auflage. Book. Sprache: Englisch.
Verlag: Springer
Erscheinungsdatum: August 2007
Seitenanzahl: 536 Seiten
Format: gebunden
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